Hideho Okada, M.D., Ph.D.
Dr. Okada is a physician-scientist who has developed therapeutic modalities in the laboratory, translated them into clinical protocols, and used his expertise as both scientist and clinician to assess the clinical data from ongoing trials. Dr. Okada’s work has consistently focused on immunotherapeutic strategies aimed at a daunting challenge in oncology – malignant brain tumors. He conducted one of the first immune gene therapy trials in patients with malignant glioma and his lab was the first to identify and fully characterize cytotoxic T-lymphocyte (CTL) epitopes for gliomas, enabling him to launch novel glioma vaccine trials in combination with poly-ICLC as an adjuvant. Dr. Okada has held four Investigational New Drug approvals for his own vaccine trials. Since 2004 to 2014, he served as a co-leader of the Brain Tumor Program within the University of Pittsburgh Cancer Institute and has worked to expand the program by developing strong interdisciplinary and translational research activities among program members. In 2010, Dr. Okada was selected to be a member of the American Society for Clinical Investigation, which is an honor society of physician-scientists, those who translate findings in the laboratory to the advancement of clinical practice.